Publications

6. Suman, P.; Fokin, M.; Hunt, K, E.; Kanger, T.; Mazzarella, D.; Ošeka, M. “Electrochemical Ferrier Rearrangement of Glycals in FlowCommun. Chem. 2026 https://doi.org/10.1038/s42004-026-01948-1

5. Qi, C.; Laktsevich-Iskryk, M.; Mazzarella, D. “Navigating electrochemical oxidative functionalization of olefins: selected mechanistic and synthetic examplesChem. Commun. 2025, 61, 4265 https://doi.org/10.1039/D4CC06306F

4. Qi, C.; Goti, G.; Sartorel, A.; Dell’Amico, L.; Mazzarella, D. “Electrochemical Ferrier Rearrangement of GlycalsOrg. Lett. 2024, 26, 9328 https://doi.org/10.1021/acs.orglett.4c03511

3. Mazzarella, D.; Qi, C.; Vanzella, M.; Sartorel, A.; Pelosi, G.; Dell’Amico, L. “Electrochemical Asymmetric Radical Functionalization of Aldehydes Enabled by a Redox ShuttleAngew. Chem. Int. Ed. 2024, 63, e202401361 https://doi.org/10.1002/anie.202401361

2. Feng, Y. L.; Zhang, B. W.; Xu, Y.; Jin, S.; Mazzarella, D.; Cao, Z. Y. “The reactivity of alkenyl boron reagents in catalytic reactions: recent advances and perspectivesOrg. Chem. Front. 2024, 11, 7249 https://doi.org/10.1039/D4QO01703J

1. Mazzarella, D. “Asymmetric Electrochemical Synthesis in FlowJ. Flow Chem. 2024, 14, 357 https://doi.org/10.1007/s41981-023-00293-x

Supervised work

18. Pulcinella, A.; Tiwari, P. C.; Luridiana, A.; Yamazaki, K.; Mazzarella, D.; Sadhoe, A. K.; Alfano, A. I.; Tieknik, E. H.; Hamlin, T. A.; Noël, T. “C1–4 Alkylation of Aryl Bromides with Light Alkanes enabled by Metallaphotocatalysis in FlowAngew. Chem. Int. Ed. 2025, 63, e202413846 https://doi.org/10.1002/anie.202413846

17. Spennacchio, M.; Bernús, M.; Stanić, J.; Mazzarella, D.; Colella, M.; Douglas, J.; Boutureira, O.; Noël, T. “A Unified Flow Strategy for the Preparation and Use of Trifluoromethyl-heteroatom AnionsScience 2024, 385, 991 https://doi.org/10.1126/science.adq2954

16. Mazzarella, D.; Stanić, J.; Bernús, M.; Mehdi, A. S.; Henderson, C. J.; Boutureira, O.; Noël, T. “In-Flow Generation of Thionyl Fluoride (SOF2) Enables the Rapid and Efficient Synthesis of Acyl Fluorides from Carboxylic AcidsJACS Au. 2024, 4, 2989 https://doi.org/10.1021/jacsau.4c00318

15. van der Heide, P.; Retini, M.; Fanini, F.; Piersanti, G.; Secci, F.; Mazzarella. D.; Noël, T.; Luridiana, A. “Giese-type alkylation of dehydroalanine derivatives via silane-mediated alkyl bromide activationBeilstein J. Org. Chem. 2024, 20, 3274 https://doi.org/10.3762/bjoc.20.271

14. Mazzarella, D.; Bortolato, T.; Pelosi, G.; Dell’Amico, L. “Photocatalytic (3+2) Dipolar Cycloadditions of Aziridines Driven by Visible-LightChem. Sci. 2024, 15, 271 https://doi.org/10.1039/D3SC05997A

13. Bernús, M.; Mazzarella, D.; Stanic, J.; Zhai, Z.; Vazquez, A. Y.; Boutureira, O.; Gargano, A.; Grossman, T.; Noël, T. “A modular flow platform enables selective and fast SuFEx ligation of small molecules, peptides, and proteinsNat. Synth. 2024, 3, 185 https://doi.org/10.1038/s44160-024-00489-6

12. Zondag, S. D. A.; Mazzarella, D.; Noël, T. “Scale-Up of Photochemical Reactions: Transitioning from Lab Scale to Industrial ProductionAnnu. Rev. Chem. Biomol. Eng. 2023, 14, 283 https://doi.org/10.1146/annurev-chembioeng-101121-074313

11. Fanini, F.; Luridiana, A.; Mazzarella, D.; Alfano, A. I.; van der Heide, P.; Rincón, J. A.; García-Losada, P.; Mateos, C.; Frederick, M. O.; Nuño, M.; Noël, T. “Flow Photochemical Giese Reaction via silane-mediated activation of alkyl bromidesTetrahedron Lett. 2023, 117, 154380 https://doi.org/10.1016/j.tetlet.2023.154380

10. Luridiana, A.; Mazzarella, D.; Capaldo, L.; Rincón, J. A.; García-Losada, P.; Mateos, C.; Frederick, M. O.; Nuño, M.; Buma, W. J.; Noël, T. “The Merger of Benzophenone HAT Photocatalysis and Silyl Radical-Induced XAT Enables Both Nickel-Catalyzed Cross-Electrophile Coupling and 1,2-Dicarbofunctionalization of OlefinsACS Catal. 2022, 12, 11216 https://doi.org/10.1021/acscatal.2c03805

9. Pulcinella, A.; Mazzarella, D.; Noël, T. “Homogeneous Catalytic C(sp3)–H Functionalization of Gaseous AlkanesChem. Commun. 2021, 57, 9956 https://doi.org/10.1039/D1CC04073A

8. Mazzarella, D.; Pulcinella, A.; Bovy, L.; Broersma, R.; Noël, T. “Rapid and Direct Photocatalytic C(sp3)−H Acylation and Arylation in FlowAngew. Chem. Int. Ed. 2021, 60, 21277 https://doi.org/10.1002/anie.202108987

7. Crisenza, G. E. M.; Faraone, A.; Gandolfo, E.; Mazzarella, D.; Melchiorre P. “Catalytic Asymmetric C–C Cross-Couplings Enabled by PhotoexcitationNat. Chem. 2021, 13, 575 https://doi.org/10.1038/s41557-021-00683-5

6. De Pedro Beato, E.; Mazzarella, D.; Balletti, M.; Melchiorre, P. “Photochemical Generation of Acyl and Carbamoyl Radicals Using a Nucleophilic Organic Catalyst: Applications and Mechanism ThereofChem. Sci. 2020, 11, 6312 https://doi.org/10.1039/D0SC02313B

5. Crisenza, G. E. M.; Mazzarella, D.; Melchiorre P. “Synthetic Methods Driven by the Photoactivity of Electron Donor-Acceptor ComplexesJ. Am. Chem. Soc. 2020, 142, 5461 https://doi.org/10.1021/jacs.0c01416

4. Mazzarella, D.; Magagnano, G.; Schweitzer-Chaput, B.; Melchiorre, P. “Photochemical Organocatalytic Borylation of Alkyl Chlorides, Bromides, and SulfonatesACS Catal. 2019, 9, 5876 https://doi.org/10.1021/acscatal.9b01482

3. Mazzarella, D.; Crisenza, G. E. M.; Melchiorre, P. “Asymmetric Photocatalytic C-H Functionalization of Toluene and DerivativesJ. Am. Chem. Soc. 2018, 140, 8439 https://doi.org/10.1021/jacs.8b05240

2. Gualandi, A.; Mazzarella, D.; Ortega-Martinez, A.; Mengozzi, L.; Calcinelli, F.; Matteucci, E.; Monti, F.; Armaroli, N.; Sambri, L.; Cozzi, P. G. “Photocatalytic Radical Alkylation of Electrophilic Olefins by Benzylic and Alkylic Zinc-SulfinatesACS Catal. 2017, 7, 5357 https://doi.org/10.1021/acscatal.7b01669

1. Kaiho, A.; Mazzarella, D.; Satake, M.; Kogo, M.; Sakai, R.; Watanabe, T. “Construction of di(trimethylolpropane) cross linkage and phenylnaphthalene structure coupled with selective β-O-4 bond cleavage for synthesizing lignin-based epoxy resins with controlled glass transition temperatureGreen Chem. 2016, 18, 6526 https://doi.org/10.1039/C6GC02211A